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diagnosis management msk orthopedics hematology clinical syndrome disease oncology radiology classification hepatology neurology table workup anemia bony cardiology criticalcare cxr
Paget's Disease of Bone • Characterized by an ↑ rate of bone turnover with both excessive
Paget's Disease of Bone ... • Caused by ( ... more (polystotic) bones ... pelvis, and long bones ... diagnosis #management #treatment
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... Generally affects long bones ... • Differentiate ... BrighamChiefs #Bone ... #diagnosis #causes
Bone Lesion on X-Ray - Differential Diagnosis Algorithm Exostotic • Osteochondroma Asymptomatic &/or Non-Active Bone Scam •
Bone Lesion on X-Ray ... /or Non-Active Bone ... • Unicameral Bone ... • Aneurysmal Bone ... #Orthopedics #Causes
Hypercalcemia - Differential Diagnosis Algorithm Elevated PTH (High or normal): • Primary Hyperparathyroidism • Familial Hypocalciuric Hypercalcemia Low
Hypercalcemia - Differential ... Diagnosis Algorithm ... Miscellaneous - Bone ... Hyperthyroid, Bony ... #causes #endocrinology
Primary Bone Tumors - Differential Diagnosis Algorithm Metastatic - Most common tumour in adults - Breast
Primary Bone Tumors ... - Differential ... • Aneurysmal Bone ... Histiocytoma #Primary #Bone ... #Orthopedics #Causes
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
inflammatory disorder of bone ... inflammation of the bones ... • Bone and joint ... Rule out other causes ... and lower jaw Treatment
Short Stature - Differential Diagnosis Algorithm Normal Variant, Normal Puberty Onset (BA = CA) • Familial Short
Diagnosis Algorithm ... Panhypopituitarism Treatment ... Chemotherapy • Bone ... Celiac, IBD) • ... endocrinology #causes
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Hemolysis - Diagnostic Algorithm ... and Causes Increased ... hyperplasia of bone ... #Differential # ... Causes #Workup #
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Diagnosis Algorithm ... stimulation (placenta/Bone ... - Highest • Bone ... Intestine - Other causes ... Renal disease - Bone
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... - Differential ... Diagnosis Algorithm ... Inflammatory: • IBD ... effect following treatment
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