62 results
Creatine Kinase - Causes of Elevated CK Levels
Acute CK Elevation (Pain > Weakness):
 • RHABDOMYOLYSIS
Creatine Kinase ... AnnKumfer #Creatine #Kinase
Immunosuppressive Strategies for the Prevention or Treatment of Acute GVHD. Panel A shows several classic immunosuppressive
inhibition of Janus kinase ... rho-associated protein kinase ... and 2, aurora A kinase ... cyclin-dependent kinase ... in which these kinases
Creatine kinase (CK) is an intracellular enzyme present in skeletal muscle, myocardium & brain; smaller amounts
Creatine kinase ... testing for creatine kinase ... ATP = creatine kinase
RHABDOMYOLYSIS
•	Characterized by skeletal muscle breakdown & necrosis. 
•	Elevated Creatine kinase (CK) hallmark of rhabdomyolysis. 
•	Defined based
Elevated Creatine kinase
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
G6PD, Pyruvate kinase
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
G6PD, pyruvate kinase
Kingella kingae
By Dr. Sara Dong @swinndong via Febrile [febrilepodcast.com  @febrilepodcast]
#ID  #Infectious Diseases  #Infections
#Microbiology
Kingella kingae
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
diseases (mevalonate kinase
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
- Tyrosine kinase
Rapid, increasing signs of extrapyramidal symptoms (EPS) is an important key feature of NMS. EPS, associated
elevated creatine kinase