49 results
Hydroxyurea - Pathophysiology and Benefits in Sickle Cell Disease
 • Decreases number of pain crises (
Hydroxyurea - Pathophysiology ... number of pain crises ... vs. 1) • Fewer ACS ... Benefits #SickleCell #pathophysiology ... #pharmacology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Angiotensin-converting enzyme (ACE ... • Exogenous (KCL ... #hyperkalemia #differential ... #diagnosis #pathophysiology ... #pharmacology #
Septic Arthritis: Pathogenesis and clinical findings
Notes:
- Septic Arthritis is typically monoarticular & the knee is involved
monoarticular & the knee ... involved in >50% of cases ... S.A. can also be caused ... pathogen across all ... SepticArthritis #pathophysiology
Causes of Aplastic Anemia

#Aplastic #Anemia #Causes #Pathophysiology #Pathology #Treatment #Management #Differential
Causes of Aplastic ... Aplastic #Anemia #Causes ... #Pathophysiology ... Pathology #Treatment #Management ... #Differential
“H’s & T’s“ - The reversible causes of Cardiac Arrest 
Hypovolemia, Hypoxia/Hypoxemia, Hydrogen Ion Excess (Acidosis),
The reversible causes ... Coronary) #HsTs #acls ... #differential # ... diagnosis #arrest #management
Drug-Induced Edema
Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
Drug-induced edema is caused ... Edema #Medication #Causes ... #Differential # ... Pharmacology #Pathophysiology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Hypochloremia - Differential ... Diagnosis Algorithm Cause ... intoxication Cause ... Hypochloremia #Differential ... Diagnosis #Algorithm #Pathophysiology
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Heart Failure Pathophysiology ... → Inflammation causes ... composite endpoint of all-cause ... heartfailure #diagnosis #management
Therapy for AL Amyloidosis 2019 
 - Antibodies (Plasma cells) 
 - Proteasome Inhibitors 
 -
Therapy for AL Amyloidosis ... Medications #Therapies #Pharmacology ... #Management #Classes
Hyperviscosity Syndrome - Causes and Treatment

 - Waldenstrom macroglobulinemia (most common) / Plasmapheresis 
 - Multiple
Hyperviscosity Syndrome - Causes ... hyperleukocytosis (AML ... Hyperviscosity #Syndrome #Causes ... #Differential # ... Diagnosis #Treatment #Management