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diagnosis clinical msk radiology potassium anthracycline benzodiazepine buckethandle bzd cardiotoxicity chemotherapy degeneration differential digoxin disease druginduced encephalopathy her2 impaired management
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Exogenous (KCL ... MunerMohamed1 #hyperkalemia ... differential #diagnosis #pathophysiology ... #pharmacology #
Drugs that Impair Renal Potassium Excretion Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine Decreased Aldosterone Synthesis: Heparin,
Aldosterone Release: ACE ... happypillsrx/ #Hyperkalemia ... #Pathophysiology ... #Pharmacology #
Osgood-Schlatter Disease - MSK Radiology Imaging Findings: • Infrapatellar fat-pad edema with loss of the patellar tendon
Disease - MSK Radiology ... DOES NOT OSD in all ... • MRI is more sensitive ... Schlatter #Disease #Knee ... patella #clinical #mri
Digoxin Pharmacology and Pathophysiology 1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... and Pathophysiology ... - Hyperkalemia ( ... #Pathophysiology ... #cardiology
Mucoid Degeneration of the ACL Imaging Findings: • T2-hyperintense fluid-signal within the enlarged ACL on both the
Degeneration of the ACL ... mucinous signal on MRI ... #degeneration #knee ... #clinical #mri ... #clinical #Radiology
Medial Meniscus Bucket Handle Tear - MSK Radiology Imaging Findings: • Truncation of the medial meniscus on
Handle Tear - MSK Radiology ... The "double PCL ... parallel to the PCL ... BucketHandle #Tear #knee ... #mri #clinical
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Blood transfusion, Hypercalcemia ... Etiology: • Pathophysiology ... Vascular narrowing on MRA ... circulation: MCA ACA
Benzodiazepine (BZD) withdrawal: clinical findings and complications • Activation of ACC and OFC -> Feelings of
Activation of ACC ... cardiac ischemia, MI ... BZD #withdrawal #pharmacology ... #pathophysiology
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity Anthracyclines cause cardiomyopathy: ✖ Reduction in left ventricular ejection fraction
receptor antagonist (MRA ... after 4 cycles for all ... Cardiotoxicity #cardiology ... #oncology #pharmacology
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