11 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... risk-stratification • Risks: infection ... only curative treatment ... #Management #treatment ... #hematology #oncology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... : Infection (sepsis ... Renal Failure Treatment ... #management #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... SLE], AOSD) • Infection ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... • Bicytopenia Treatment ... : • Infection ... #management #treatment ... #hematology
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... Arterial blood gas (ABC ... ) on room air Treatment ... #diagnosis #management ... #treatment #hepatology
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
(HES) - Diagnosis ... and Management ... eosinophil count (AEC ... hypersensitivity - Infection ... #hematology #differential
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Capillary leak syndrome ... edema, compartment syndrome ... flares: • No effective ... #diagnosis #management ... #rheumatology
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
and Management ... sex • Metabolic syndrome ... forefoot, ankles, knees ... concomitant infection ... #management #treatment
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
fast bacterial infection ... Histopathological Diagnoses ... Hypoalbuminemia Treatment ... agonists #TAFRO #diagnosis ... #management #rheumatology
Relapsing Polychondritis

What is it?
Recurrent inflammation of the cartilage in the body (Autoimmune disorder)

Who?
• Most frequently: 40
Bacterial ○ Viral infection ... /EGPA • RA Diagnosis ... affected tissue Treatment ... Polychondritis #rheumatology ... #diagnosis #management