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syndrome workup anesthesiology checklist hematology differential disease erythematosus intraoperative neurology summary systemic dermatology druginduced hyperthermia symptoms thrombocytopenia activation acute anaphylaxis
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... Positive in 60-80% of cases ... life-threatening • Treatment ... Erythematosus #Diagnosis ... #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Initial screening test ... severe disease Treatment ... #Summary #diagnosis ... #rheumatology # ... management
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... autoantibodies that will cause ... Erythematosus #SLE ... CNS #neurology #rheumatology ... #management #treatment
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... life-threatening • Treatment ... Usual therapeutic management ... #table #rheumatology ... #diagnosis #management
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... if < 200ng/mL Best ... #rheumatology # ... pharmacology #levels #lupus ... #management
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
Treatment depends ... hyperthermia crisis (late sign ... Anesthesiology #Anesthesia ... #Checklist #Diagnosis ... #Management #Workup
Cardiac Tamponade - Guidelines for Crises in Anaesthesia Caused by an accumulation of blood, pus, effusion fluid
• Diagnostic ... thoracotomy is a better treatment ... examination and vital signs ... Plan definitive management ... #Management #Workup
Malignant Hyperthermia Crisis - Guidelines for Crises in Anaesthesia Unexplained increase in ETCO2 AND tachycardia AND increased
rise is a late sign ... other, more common causes ... ❹ Call for MH treatment ... Intraoperative #Checklist #Diagnosis ... #Management #Workup
Intraoperative Anaphylaxis - Guidelines for Crises in Anaesthesia • Unexplained hypotension • Unexplained bronchospasm (wheeze may be absent
of more of the signs ... trolley, anaphylaxis treatment ... require prolonged treatment ... Intraoperative #Checklist #Diagnosis ... #Management #Workup
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
rheumatoid arthritis, SLE ... /Edrophonium test ... - Cogan sign ... - Peek sign 2. ... #management #neurology
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