23 results
Kidney Biopsy - Diagnosis Algorithms
1) Normal Glomerulus by LM
2) Glomerular Crescents
3) Double Contours of GBM
4) Endocapillary
Double Contours of GBM ... Diagnosis #Algorithm #nephrology ... #pathology
Spectrum of Glomerular Diseases
Nephrotic - Mechanism:
 • Injury to podocytes
 • Changed architecture: Scanning. Deposition of
Deposition of matrix ... • Breaks in GBM ... spectrum #diagnosis #nephrology
This image shows portions of glomerular tuft with collapsed GBM (across top), spicular amyloid (middle right),
with collapsed GBM ... #glomerulus #GBM ... #amyloid #desposition ... SEM #clinical #nephrology ... #pathology
Stage III Glomerulonephritis on Electron Microscopy
This image shows acellular scanning EM from a biopsy with membranous
acellular scanning EM ... more extensive GBM ... surface of reticular GBM ... #MGN #stage3 #GBM ... #pathology
Stage II Membranous Glomerulonephritis on Electron Microscopy
This eyeSCANdy image shows acellular scanning EM of a glomerulus
acellular scanning EM ... appearance of GBM ... #MGN #stage2 #GBM ... SEM #clinical #nephrology ... #pathology
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
Basement Membrane (GBM ... Linear, ribbon-like GBM ... staining on IF • No EM ... Differential #Diagnosis #Nephrology
This image shows acellular scanning EM showing glomerular basement membrane duplication at high power in a
acellular scanning EM ... arkanalabs #GBM ... SEM #clinical #nephrology ... #pathology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
• Complement deposition ... complement of lg deposition ... immune deposits on EM ... Glomerulonephritis #MPGN #nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
proliferative • Anti-GBM ... • Protein deposition ... #Proteinuria #Nephrology
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
Glomerulonephritis • Anti-GBM ... Immune-complex deposition ... #KidneyInjury #Nephrology