25 results
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... more specific for hepatic ... • R value = (ALT ... #Enzymes #LFTs ... Transaminitis #diagnosis #differential
Reference Laboratory Values - Fishbone Shorthand
Complete Blood Count (CBC), Basic Metabolic Panel (BMP), Liver Function Tests
Reference Laboratory ... Values - Fishbone ... Metabolic Panel (BMP), Liver ... Function Tests (LFTs ... #Values #Labs #
Evaluation abnormal liver tests in pregnancy
- Cholestatic Pattern
- Hepatocellular Pattern

#LFTs #transaminits #pregnancy #obgyn #obstetrics #hepatology #diagnosis
Evaluation abnormal liver ... in pregnancy - Cholestatic ... Hepatocellular Pattern #LFTs ... hepatology #diagnosis #differential
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
(LFTs) Elevation ... ALT ≥ 3x ULN Cholestatic ... ALP ≥ 2x ULN R Value ... pattern ≤2: Cholestatic ... #FunctionTest #LFTs
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... R-value: Serum ... replaced by non-hepatic ... chemistry #diagnosis #differential ... transaminitis #LFTs
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
(LFTs) - Normal ... Values and Interpretation ... , intrahepatic cholestasis ... Function #Tests #LFTs ... #Laboratory #Values
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Tests (LFTs) - ... Differential Diagnosis ... ) • Non-hepatic ... Function #Tests #LFTs ... #Differential #
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Injury - Differential ... Vasculature • Hepatic ... Congestion/CHF • Hepatic ... Hepatitis, TB Cholestatic ... #Injury #Differential
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Chronic - ongoing ↑ LFTs ... or symptoms of liver ... Calculate R-Value ... Mixed DILI • Cholestatic ... Idiosyncratic #differential
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Injury: • Hepatic ... Venoocclusive disease • Hepatic ... epithelia: - Cholestasis ... injury #hepatitis #differential