117 results
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
pericarditis • Hematologic ... proteins domain: Low ... C3 or low C4, Low ... C3 and low C4 ... Erythematosus #diagnosis #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... thrombosis and/or blood-brain ... Puncture, EEG Treatment ... CNS #neurology #rheumatology ... diagnosis #management #treatment
Rheumatoid Arthritis - ACR 2021 Guidelines
 - Low Disease Activity
 - Moderate to High Disease Activity
Guidelines - Low ... Tapering DMARDs - Treatment ... Guidelines #management #treatment ... #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... , oral ulcers, Lupus ... 60-80% - Low ... life-threatening • Treatment ... Management #Summary #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... staining): • Low ... Post-strep GN, Lupus ... diagnosis #algorithm #rheumatology
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus
Clinical and Immunologic Criteria

CLINICAL CRITERIA
 - ACUTE CUTANEOUS LUPUS
Criteria - Systemic Lupus ... ACUTE CUTANEOUS LUPUS ... CHRONIC CUTANEOUS LUPUS ... anticoagulant - Low ... #Diagnosis #Rheumatology
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
S - Systemic Lupus ... Hypocomplementemia #Low ... #differential #hematology
Thromboelastography (TEG) based therapy and Management

If r time prolonged -> FFP
If MA low -> plts/cryoprecipitate (if
-> FFP If MA low ... Management #Diagnosis #Hematology ... Thromboelastogram #Treatment
Thromboelastography (TEG) Based Management
 - If R time prolonged -> FFP 
 - If MA low
FFP - If MA low ... TEG #Management #treatment ... #diagnosis #hematology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
in >90% - Low ... constitutional symptoms • Treatment ... 60-80% - Low ... life-threatening • Treatment ... comparison #table #rheumatology