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diagnosis hematology differential causes bruising dic disseminated interpretation intravascular workup abnormal aptt blanching bruise chemistry disease disorders ecchymosis hematomas hemorrhage
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
(INR), Normal PTT ... , Normal PT (INR ... #Prolonged #PPT ... #Diagnosis #Algorithm ... Causes #Hematology #coagulation
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Intravascular Coagulation ... Findings: • Bleeding ... venipuncture sites Laboratory ... Thrombocytopenia - Normal ... - APTT < 1.5 x normal
Algorithm for Investigation of Abnormal Coagulation Tests - Prolonged PT - Prolonged aPTT and Prolonged PT - Prolonged aPTT Dr.
Algorithm for Investigation ... of Abnormal Coagulation ... DrEricStrong #Algorithm ... #Coagulation #Abnormal ... #APTT #Laboratory
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
inhibitor of a coagulation ... PT/NORMAL PTT: ... PT/ABNORMAL PTT ... /NORMAL PTT: Suggests ... PT/ABNORMAL PTT
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Differential Diagnosis Algorithm ... Destruction • Abnormal ... #Bleeding #Bruising ... Differential #Diagnosis #Algorithm
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC) Platelet count: • Expected: Low (or normal) • Elevation
Intravascular Coagulation ... platelet aggregation PT ... consumption of coagulation ... using INR use PT ... diagnosis #hematology #laboratory
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
common inherited bleeding ... • Prolonged bleeding ... GI. uterine) Laboratory ... • Normal platelet ... PT/INR • Normal
Normal Thromboelastogram - Specific parameters represent the 3 phases of the cell-based model of haemostasis: initiation,
Normal Thromboelastogram ... Diagnosis #Hematology #Coagulation ... #Thromboelastogram ... #TEG #Normal #Interpretation ... #Laboratory
Bleeding manifestations Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
are typical of coagulation ... Type O blood normally ... levels tend to be normal ... , PT should be normal ... Measurement of coagulation
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm Blood Loss: >500mL post vaginal delivery OR >1000 mL
Differential Diagnosis Algorithm ... succenturiate lobe • Abnormal ... intravascular coagulation ... (DIC) • Anti-coagulation ... PostPartum #Hemorrhage #PPH
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