8 results
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... Differential Diagnosis Algorithm ... Destruction • Abnormal ... Disordered Platelet Function ... Iatrogenic) • Liver
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
Liver Function Tests ... (LFTs) - Normal ... Values and Interpretation ... #Function #Tests ... #LFTs #Laboratory
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
inhibitor of a coagulation ... PT/ABNORMAL PTT ... intravascular coagulation ... function tests ... fibrinogen levels, and testing
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Intravascular Coagulation ... venipuncture sites Laboratory ... Thrombocytopenia - Normal ... DIC • Severe Liver ... - APTT < 1.5 x normal
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
- Interpretation ... - If both are normal ... • Albumin • Coagulation ... RBC (hemolysis, bleeding ... #LFTs #RValue #interpretation
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... tests algorithm ... initial response to abnormal ... decision for repeat testing ... #Algorithm #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Differential Diagnosis Algorithm ... Tests of synthetic function ... may be abnormal ... RBC (hemolysis, bleeding ... differential #diagnosis #algorithm
Oral anticoagulants and reversal/hemostatic strategies. 

In the elegant tug-of-war between thrombosis and hemostasis, prescribing an anticoagulant
is essentially telling ... polite memo to the liver ... Andexanet alfa, which function ... negotiation with a coagulation ... #Plasma #FFP #Bleeding