25 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Angiotensin-converting enzyme (ACE ... • Synthesis of aldosterone ... Trimethoprim) • Aldosterone ... • Exogenous (KCL ... pathophysiology #pharmacology
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Pentamidine Decreased Aldosterone ... Ketoconazole Decreased Aldosterone ... Release: ACE inhibitors ... , K-ATPase and Aldosterone ... Pathophysiology #Pharmacology
Here’s a review of the Renin-Angiotensin-Aldosterone system (RAAS)

This is a very common pathway that clinicians should
Here’s a review ... Renin-Angiotensin-Aldosterone ... Antagonists), all ... potassium, just like all ... ReninAngiotensinAldosteroneSystem #RAAS #Pharmacology
Diuretic Electrolyte Excretion Effects 
Diuresis, Na+, K+, Mg2+, Ca2+, Cl-, HCO3-, Uric Acid
 - Thiazide Type
+, Mg2+, Ca2+, Cl ... Type - Loop - Aldosterone ... electrolytes #effects #pharmacology
Lidocaine HCl - sodium channel blocker. Local anesthetic and class 1B antiarrhythmic. Originally developed in 1943
Lidocaine HCl - ... #Pharmacology #Lidocaine ... Xylocaine #Systemic #Review
Lisinopril - ACE inhibitor used for the treatment of hypertension and heart failure. 3rd most prescribed
Lisinopril - ACE ... #Pharmacology #Lisinopril ... Inhibitor #Overview #Review
Linezolid (Zyvox) (PO and IV) - Antibiotics Class Overview

Mechanism: Oxazolidinone class –unique ribosomal inhibitor (acts on
Spectrum: covers all ... infections #Pharmacology ... #Antibiotics #Review
Aminoglycosides  - Antibiotics Class Overview

Gentamicin, Tobramycin, Amikacin, Streptomycin -30S inhibitor (all IV)
Spectrum: Extremely efficacious vs.
30S inhibitor (all ... #Pharmacology #Antibiotics ... #Review #Overview
Antifungal Echinocandins  - Antibiotics Class Overview

Mechanism: Inhibit glucan synthesis in fungal cell wall by blocking
All are IV only. ... covers virtually all ... initial monotherapy) All ... Anidulafungin #Pharmacology ... #Antibiotics #Review
Vancomycin and Dalbavancin (lipoglycopeptide antibiotics) - Antibiotics Class Overview

Mechanism: Glycopeptide -  inhibits cell wall synthesis
Used for: all sorts ... #Pharmacology #Antibiotics ... #Review #Overview