13 results
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
) = {Na - (Cl + ... Acetazolamide Causes ... Volume depletion (diuresis ... Diagnosis #Summary #Nephrology ... #ABG #bloodgas
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... • Inhibit Na+ Cl ... loss through the nephron ... #Pharmacology # ... nephrology #conversion
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic ... intake, Diuretics ... -: Diuretics, Bartter ... Diagnosis #Algorithm #Nephrology ... #Causes
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Kidney loss of Cl ... loop or thiazide diuretics ... pressure: Active diuretic ... the indicated causes ... urine #Algorithm #nephrology
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Non-anion Gap Metabolic ... Generalized distal nephron ... Potassium-sparing diuretics ... ACE-Is and ARBs ... #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Diuretics and Agents ... resistance • Metabolic ... Inhibitors of Na+K+2Cl ... Kidney stones caused ... #Nephrology #Pharmacology
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Segments of the Nephron ... organic acids and bases ... acid and most diuretics ... vasopressin control #Nephron ... Tubules #Table #Pharmacology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Weakness, cramping, nausea ... (Assess GFR), ±VBG ... only if no clear cause ... Ca-gluconate or 1g CaCl ... Treatment #potassium #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
• K sparing diuretics ... • NSAIDs • ACE ... infusions) - Metabolic ... differential #diagnosis #causes ... potassium #high #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic ... intake, Diuretics ... -: Diuretics, Bartter ... Diagnosis #Algorithm #Nephrology ... #Causes