10 results
Diuretics sites of action on the nephron
1) Acetazolamide (carbonic anhydrase inhibitor)
2) Osmotic diuretics (e.g. mannitol)
3) Loop
Diuretics sites ... action on the nephron ... triamterene) #nephron ... #diuretics #pharmacology ... #nephrology #medications
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... • Inhibit Na+ Cl ... loss through the nephron ... #Pharmacology # ... nephrology #conversion
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
ABG And BMP Normal ... ) = {Na - (Cl + ... Volume depletion (diuresis ... Diagnosis #Summary #Nephrology ... #ABG #bloodgas
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Diuretics and Agents ... resistance • Metabolic ... Inhibitors of Na+K+2Cl ... #Nephrology #Pharmacology ... #Medications #Table
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Non-anion Gap Metabolic ... Generalized distal nephron ... Potassium-sparing diuretics ... ACE-Is and ARBs ... diagnosis #causes #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Etiology: • Medications ... (Assess GFR), ±VBG ... STOP offending medications ... Ca-gluconate or 1g CaCl ... Treatment #potassium #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
• K sparing diuretics ... • NSAIDs • ACE ... infusions) - Metabolic ... Medications 2. ... potassium #high #nephrology
Continuous Renal Replacement Therapy (CRRT) - Overview
Types of CRRT
 • CVVHD - Continuous Veno-Venous hemodialysis -
volume overload; diuretic ... CRRT Specific Indications ... correction of metabolic ... 4K, 2K, or 0K (all ... #Nephrology #Management
Effects of Prostaglandins and NSAIDs on the Kidney
Effects of Prostaglandins on the Kidney:
 • The vasodilatory
hormones that act ... increased in CKD ag ... perfusion of remaining nephrons ... Kidney #renal #nephrology ... #pharmacology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
• K sparing diuretics ... • NSAIDs • ACE ... infusions) - Metabolic ... Medications 2. ... potassium #high #nephrology