59 results
Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
: when any egg of ... Signs / Symptoms ... Neurological Compromise (e.g ... Cardiac Compromise (e.g ... #Anaphylaxis #pathophysiology
Short Stature - Differential Diagnosis Algorithm
Normal Variant, Normal Puberty Onset (BA = CA)
 • Familial Short
Differential Diagnosis ... Dysplasias • (e.g ... Disease • GI (e.g ... • CNS Tumors (e.g ... #ShortStature #Differential
Approach to ECGs - Syncope Syndromes
Electrolytes
 • ↑K - brady, peak T, wide QRS, no P,
Approach to ECGs ... - Syncope Syndromes ... mchlwng #Syncope #Syndromes ... #ECG #EKG #Checklist ... electrocardiogram #differential
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
to Headaches - Differential ... papilledema • Horner syndrome ... ) • Systemic symptoms ... and signs (e.g. ... CNS infection (e.g
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... WBC >100k, + lab signs ... : • Pathophysiology ... unless worrisome EKG
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... /Symptoms: • GH ... deficiency: - Short ... tissue expansion (e.g ... endocrinology #pathophysiology
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... =>Prader-Willi Syndrome ... Signs/Symptoms ... fractures • Short ... #genetics #pathophysiology
Irritable Bowel Syndrome (IBS) - Pathophysiology, Diagnosis and Management Algorithm
Risk factors: Previous acute enteric infection, Female
Irritable Bowel Syndrome ... (IBS) - Pathophysiology ... (e.g. fibromyalgia ... factors affecting symptom ... #Pathophysiology
Approach to ECGs - Ischemia
MI = Biomarkers + ECG or echo/angiogram findings
Pathologic Q - 1/3 height
= Biomarkers + ECG ... Equivalents / Don't Miss Signs ... #Ischemia #ECG ... #EKG #diagnosis ... Interpretation #differential
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Signs and symptoms ... Radiographic findings (eg ... Laboratory findings (eg ... VEP’s: EEG of visual