16 results
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal Syndrome ... Pulmonary Renal Syndromes ... Systemic lupus erythematosus ... biopsy By Tess Litchman ... differential #diagnosis #nephrology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... block • Sjogren syndrome ... polymyositis overlap syndrome ... Hydroxychloroquine *Short ... #rheumatology #management
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
Scotoma, Ocular pain ... /pain upon eye movement ... Systemic lupus erythematosus ... , Sjögren syndrome ... Manifestations #diagnosis #neurology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
lymphoma • Evans' syndrome ... lymphoproliferative syndrome ... Shrinking lung syndrome ... Arthritis: • Joint pain ... • Malar rash - spares
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Systemic Lupus Erythematosus ... Demyelinating Syndrome ... Systemic #Lupus #Erythematosus ... #SLE #CNS #neurology ... cerebritis #diagnosis #management
Mechanisms of Pain
Mixed - Nociceptive/Neuropathic
Nociceptive - Tissue Damage
 - Visceral - (From organ/cavity lining) Poorly localized,
Mechanisms of Pain ... Well-localized, sharp, short ... Complex regional pain ... syndrome - Deafferentation ... #Mechanisms #Neurology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... • Weakness: Starts ... Hands or feet • Pain ... #diagnosis #management ... #treatment #neurology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... Systemic lupus erythematosus ... • Fever is the main ... systemic lupus erythematosus ... #Diagnosis #Management
Ear Pain (Otalgia) - Differential Diagnosis Framework

Primary Otalgia 
 - Pain that originates from the ear
- Ramsay Hunt syndrome ... Relapsing, bilateral, erythematous ... Temporomandibular joint syndrome ... Nerve V: • TMJ syndrome ... vision or black spots
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO syndrome is ... lesions + Rheumatic pain ... thickening • Osteitis: pain ... anterior chest wall, parts ... Rheumatology #diagnosis #management