13 results
Adie's Pupil
What? Unknown nature & benign
 • Regular and mildly dilated pupil (4-6mm);
 • Light-near dissociaton;
Holmes-Adie Syndrome ... females Differential Diagnosis ... : • CN Ill Palsy ... dissociation • Other causes ... #PhysicalExam #neurology
Localizing Extraocular Movement Disorders
 • CN Ill (Oculomotor) Nerve Palsy 
 • CN IV (Trochlear) Nerve
Disorders • CN ... • CN IV (Trochlear ... • CN VI (Abducens ... One-and-a-half Syndrome ... ophthalmology #neurology
Anisocoria Evaluation Flow Chart - Differential Diagnosis
1. Check pupillary reaction to light 
2. Measure pupil size.
- Horner's Syndrome ... Anisocoria - CN ... III Palsy - Pharmacologic ... Dilatation - Adie's ... Anisocoria #Evaluation #Algorithm
Alice in Wonderland Syndrome
What? Metamorphophsia - Distortions of the visual perceptions with changes in size (micro
in Wonderland Syndrome ... macropsia), color, movement ... • CNS: parietal ... (Many causes!) ... #diagnosis #neurology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
CNS Infection in ... HIV-Associated CNS ... Infections: • Most CNS ... • CNS opportunistic ... 100% Primary CNS
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... , Headache, Movement ... Erythematosus #SLE #CNS ... #neurology #rheumatology
Hyponatremia - Differential Diagnosis Algorithm
Hypovolemic - Give volume
Hypervolemic (Edematous) - Look for and treat underlying cause
Algorithm Hypovolemic ... cirrhosis, nephrotic syndrome ... Pulmonary Diseases, CNS ... #Algorithm #diagnosis ... #nephrology #sodium
Diplopia - Double Vision - Differential Diagnosis Algorithm
Clinical Pearls:
 • Diplopia is almost always binocular.
 •
CN VI palsy ... for ptosis with CN ... Ill palsy ... • Neurologic ... #Algorithm #Causes
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
/pain upon eye movement ... involvement: Intractable nausea ... pain • Extra-CNS ... Manifestations #diagnosis ... #neurology #symptoms
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
and infects the CNS ... mononuclear cells in the CNS ... Diagnosis: MRI ... The clinical syndrome ... dysfunction like gait