10 results
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Differential Diagnosis Algorithm ... Intestine - Other causes ... Most common symptoms ... disease - Bone symptoms ... duct stricture/Stones
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
• recurrent fractures ... collection with EDTA Pathophysiology ... mineralization Symptoms ... pain - Frequent fractures ... Phosphatase: • Other causes
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings

 • Primary (Idiopathic): Unknown etiology, but associated
, humeral head fracture ... a stroke that caused ... FrozenShoulder #pathophysiology ... #diagnosis #symptoms ... #staging #msk
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
Greater Trochanter Fracture ... Trendelenburg #Gait #pathophysiology ... #causes #symptoms ... signs #diagnosis #msk
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... lymphocyte predominant (LP ... pattern of spread, B symptoms ... Amy Chung, MD, MSc ... Classification #pathophysiology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
findings: • Symptoms ... compression by fractured ... Non-compressive Spinal Cord Causes ... hypercoagulable states ... differential #algorithm
Fracture Healing (and disruptors of this process)
Inflammatory Stage (0-7d)
 • Fracture disrupts local blood vessels ->
Inflammatory Stage ... site Soft Callus Stage ... Fluoroquinolones - Causes ... #msk #Staging # ... pathophysiology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
peaks between the ages ... 10-33% develop MS ... monophasic Pathophysiology ... Bilateral signs and/or symptoms ... • Infectious causes
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
bone formation MSK ... -> Pathologic fractures ... Nephrolithiasis (Kidney Stones ... PagetsDisease #pathophysiology ... diagnosis #signs #symptoms
Extensor Carpi Ulnaris (ECU) subluxation 
The Extensor Carpi Ulnaris (ECU), is the must ulnar of the
What causes ECU ... What are the symptoms ... wrist and locate all ... during the initial stage ... Orthopedics #Wrist #msk