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diagnosis rheumatology treatment differential hemophagocytic hlh lymphohistiocytosis pulmonary abscess bullous classification coagulation crisis cryoglobulinemia cryoglobulinemic dermatology dic disseminated hemeonc intravascular
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Autoimmune ANCA vasculitis ... palpable purpura 2/2 vasculitis ... coagulopathy) • CBC ... Goodpasture's cause ... differential #diagnosis #management
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group < 5%
- Diagnosis, causes ... and management ... Clinical manifestations ... with purpura - Renal ... #Rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
pulmonary and renal ... • Microscopic Polyangiitis ... tract, and often causes ... Lab Tests: • CBC ... • Urinalysis (Renal
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
• Most common cause ... Lung Abscess Pathophysiology ... Lung Abscess - Clinical ... Diagnosis: • Vasculitis ... Granulomatosis with polyangiitis
Bullous Pemphigoid - Diagnosis and Management Summary Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Summary Pathophysiology ... epidermis from dermis Clinical ... - Erosions and crusts ... not feasible CMC ... #dermatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... accumulation of clinical ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... organ damage Clinical ... Bleeding (64%) • Renal ... #treatment #management ... #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... /aggregate) of CD4 ... salivary ducts Clinical ... Distal (Type I) renal ... #Diagnosis #Management
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
Crisis (SRC) Clinical ... anemia (MAHA) Pathophysiology ... of arteries Management ... • Refractory cases ... #Crisis #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome caused ... Clinical Presentation ... Pathophysiology ... of NK cells and CD8 ... #Hematology #HemeOnc
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