7 results
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... and Pregnancy ... @Bloodman #Thrombocytopenia ... #HELLP #AFLP #Obstetrics ... #OBGyn #Hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... (AFLP) Three syndromes ... #Thrombocytopenia ... TTPHUS #HELLP #AFLP ... #obstetrics #hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Fatty Liver of Pregnancy ... (AFLP) Pathophysiology ... iMedEducation #AFLP ... #hepatology #obstetrics ... #obgyn #diagnosis
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in Pregnancy ... features: Hemolysis, Thrombocytopenia ... (AFLP) • Onset ... #hepatology #obstetrics ... diagnosis #icp #HELLP #AFLP
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
transfusion • Thrombocytopenia ... protein C and S Pathophysiology ... venipuncture sites Laboratory ... coagulopathy - Thrombocytopenia ... treatment #management #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Intravenous Drug Use • Pregnancy ... Heparin-induced thrombocytopenia ... Venous #Arterial #pathophysiology ... #hematology #differential
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... obstruction • ALP ... cholestasis of pregnancy ... diagnosis #workup #hepatology