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diagnosis management differential algorithm causes oncology primary syndrome biliary chronic workup anemia atlas cholangitis classification cll comparison gastroenterology hbv hepatitis
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis #pathophysiology #pbc #psc #hepatology #comparison
Cholestatic Liver ... Disease: Primary ... Biliary Cirrhosis ... Cholangitis #pathophysiology ... #pbc #psc #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary Cirrhosis ... Pathophysiology ... /Liver failure ... or higher • Liver ... diagnosis #workup #hepatology
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Primary Biliary Cirrhosis ... of autoimmune disease ... Liver biopsy findings ... #Biliary #Cirrhosis ... Diagnosis #Algorithm #hepatology
Primary Biliary Cirrhosis - Pathophysiology Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish Epigentics Risk
Primary Biliary Cirrhosis ... of autoimmune disease ... relative with PBC ... Cholestasis #PBC ... #hepatology
Mechanisms Driving Increased Thrombosis and Bleeding in Liver Disease Increased Thrombosis Increased Platelet-Vesset Wall Interaction •
and Bleeding in Liver ... Disease Increased ... Bleeding #Clot #Cirrhosis ... #Pathophysiology ... #Hepatology #Liver
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Folate deficiency, Liver ... Abetalipoproteinemia, Liver ... Artifact, Uremia, Liver ... stomatocytosis, Liver ... differential #diagnosis #hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Venoocclusive disease ... Hereditary: Wilson Disease ... disease: > 2 ... hepatitis: < 1 • Cirrhosis ... diagnosis #algorithm #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
those with CLD (± cirrhosis ... months without treatment ... disease, liver ... #Failure #Cirrhosis ... #Hepatology #gastroenterology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Artifact (redo CBC ... disorders • Celiac disease ... Non malignant hematologic ... effect following treatment ... Algorithm #Causes #Hematology
The 6 C’s of Primary Sclerosing Cholangitis (PSC) PSC is a chronic, cholestatic, immune-mediated disease characterized by
• CIRRHOSIS - ... Progression to cirrhosis ... indications for liver ... and end-stage liver ... management #summary #Hepatology
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