11 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... Renal Failure Treatment ... • Steroids: IV ... diagnosis #management #hematology
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
dementia Pathophysiology ... is similar to PML ... Treatment: • HAART ... treatment • Cognitive ... dementia #AIDS #Neurology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
pathogens, including PML ... Antimicrobial treatment ... status, and focal neurologic ... confusion, and focal neurologic ... InfectiousDiseases #Neurology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... : 2 hit mechanism ... : 33% • Treatment ... transfusion • Pathophysiology ... : No • Treatment
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Thrombocytopenia (HIT ... ♀, ↑Age, ESRD Pathophysiology ... #HIT #Heparin ... Diagnosis #Management #Treatment ... #Hematology #HemeOnc
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Pathophysiology ... Campylobacter jejuni - HIV ... Treatment: • Plasmapheresis ... diagnosis #management #treatment ... #neurology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... deficiency) • HIT ... + Bleeding Treatment ... diagnosis #causes #treatment ... #management #hematology
Hepatic Encephalopathy - Diagnosis and Management Summary
Definition:
 • Alteration in brain function manifested by neuropsychiatric symptoms
other causes of neurologic ... noxious stimuli) TREATMENT ... Initiate empiric treatment ... supplementation, IV ... #hepatology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
immunodeficiency virus (HIV ... the underlying pathophysiology ... and cauda equina TREATMENT ... diagnosis #management #neurology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... diagnosis column Treatment ... motor neurons - IV ... Lateral #Sclerosis #neurology