10 results
Lactulose: Mechanism of Action in Hepatic Encephalopathy
Lactulose → ↑ Lactic Acid, Acetic Acid → ↓ pH
: Mechanism of Action ... , Acetic Acid → ... #Lactulose #pharmacology ... mechanism #ammonia #hepatology ... #pathophysiology
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Anticoagulant Sites of Action ... #Medications #Pharmacology ... #Pathophysiology ... Mechanisms #DOAC #Hematology
Mechanism of Action of Bile Acid Sequestrants
Bile Acid Sequestrants → ↓ Hepatic Bile Acid Pool →
Mechanism of Action ... ↓ Hepatic Bile Acid ... ↑ Hepatic Bile Acid ... sequestration #pathophysiology ... #pharmacology #
Tranexamic Acid: Mechanism of Action
 - TXA is an anti-fibrinolytic
 - TXA is a synthetic analog
Tranexamic Acid: ... Mechanism of Action ... analog of the amino acid ... #pathophysiology ... #hematology #TXA
Here is a quick guide on the common direct-acting antivirals (DAAs) for chronic hepatitis C virus
common direct-acting ... #medications #infectiousdisease ... #hepatology #HepC ... HepatitisC #Management #Pharmacology
Role of Uric Acid in the Inflammation of Gout

Allopurinol, Febuxostat - Xanthine oxidase
Colchicine - Release of
Role of Uric Acid ... gout #uricacid #pathophysiology ... #pharmacology # ... rheumatology
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
Tranexamic Acid ... Indications and Pharmacology ... • Duration of Action ... TXA #Tranexamic #Acid ... #hematology
Antifungal Coverage Activity Antibiogram 

Spectrum of action of systemic antifungal agents. Solid blocks represent species in
Spectrum of action ... amphotericin; ANID ... Echinocandins #Pharmacology ... #InfectiousDiseases
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
including uric acid ... Henle's loop (TAL) - Active ... tubule (DCT) - Active ... Segments #Function #Pathophysiology ... Tubules #Table #Pharmacology
Allopurinol Pharmacology Summary

Xanthine oxidase inhibitor blocking the formation of new uric acid
Initiate 1-2 days prior to
Allopurinol Pharmacology ... formation of new uric acid ... Slow onset of action ... pre-formed uric acid ... #pathophysiology