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Intraoperative Sepsis - Guidelines for Crises in Anaesthesia Severe sepsis (hypotension persisting after initial fluid challenge of
30ml.kg-1 or blood lactate ... including blood gas, lactate ... Check serial lactates ... Discuss ongoing management ... Checklist #Diagnosis #Management
SEPSIS AND SEPTIC SHOCK DEFINITION AND PATHOPHYSIOLOGY • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
= 65 mm Hg and lactate ... INITIAL MANAGEMENT ... • Lactated Ringers ... ADVANCED MANAGEMENT ... Shock #Diagnosis #Management
Algorithm in Suspected Bacterial Peritonitis - Infographic by IDagram @ID_agram Runyon Criteria for Secondary Peritonitis (two of the
50 mg/dL - and lactate ... Algorithm #Diagnosis #Management
Shock - Differential Diagnosis Framework - MAP <65. SBP <90, drop in SBP > 40 -
malperfusion - Lactate ... MAP > 60-65 2) Lactate ... algorithm #treatment #management
Metformin Associated Lactic Acidosis (MALA) Pathophysiology of MALA - Metformin interferes with the activity of the
recycles peripheral lactate ... production  increased lactate ... Toxicology #Diagnosis #Management
Salicylate Toxicity - Diagnosis and Management Consider if: 1) Patient is hot and altered 2) You see tachypnea with
Diagnosis and Management ... Alkalosis, High Lactate ... Level: 150mg/kg Management ... Toxicology #diagnosis #management
Systemic Inflammatory Response Syndrome (SIRS) • Non-specific (infections vs non-infectious) • ≥2 of the following: o Temp >38°C or <36°C o HR >90 bpm o RR
o Lactate >2 mmol ... /L Management ... #sirs #shock #lactate
Toxic Alcohol Ingestion: Isopropyl Alcohol General concepts for toxic alcohols: • Parent compounds (not metabolites) cause high osmolal
pyruvate converts to lactate ... #Diagnosis #Management
Sepsis - Diagnosis and Management Life-threatening organ dysfunction caused by a dysregulated host response to infection SEPTIC SHOCK
Diagnosis and Management ... Serum lactate >2 ... in-hospital mortality Management ... Criteria #Diagnosis #Management
Shock - Diagnosis and Management Summary • Hypotension: SBP<90, SBP drop >40, MAP<65 (Normotension, HTN possible
Diagnosis and Management ... ) • Elevated lactate ... Shock #Diagnosis #Management
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