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Leigh Syndrome History: 19-month-old girl with hypotonia, developmental delay, failure to thrive, and bilateral optic disc
Leigh Syndrome ... MarkMamloukMD #Leigh
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
or AST > ALP): ... • Severe - ALT ... Viral, Ischemia, AIH ... • Moderate - ALT ... or AST): • US
Amiodarone induced thyroid changes Histopath: Remarkably enlarged follicles, distended with colloid, without scalloping, and lined by flattened
lipofuscin) AIT ... are two types of AIT ... pertechnetate scanning Weigh ... thyrotoxicosis #AIT
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Injury • AST ... /ALT elevation > ... Alk phos • ALT ... and kidney) Is it ... • R value = (ALT
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
R-value: Serum (ALT ... /ULN ALT) / (Alk ... to liver than ALT ... : ↑ • ALT: ↑ ... /ALT: typical of
Features of Components of Liver Function Tests #Diagnosis #IM #GI #LFTs #Liver #Function #Tests #Locations #AlkPhos
Locations #AlkPhos #AST ... #ALT #Ddxof
CPAP Troubleshooting Tips 1. Wrong size/style mask → try a different mask, nasal pillows 2. Trouble getting used
getting used to it ... tolerating forced air ... mask up to face at ... face mask, check fit ... noise → check air
Standardized Physical Abuse Guideline <6 months of age • Social work consult • Skeletal survey • Head
survey • Head CT, AST ... , ALT, lipase ... Abdominal CT if AST ... months of age if AST ... or ALT> 80, signs
Clinical Diagnosis of Autoimmune Hepatitis - Onset of jaundice within prior 8 weeks - Ongoing consumption
of jaundice - AST ... >50, AST/ALT >1.5 ... or >400 IU/L, AST ... /ALT <1.5), ANA ... Diagnosis #Hepatology #AIH
Liver Function Tests (LFTs) - Aspartate aminotransferase (AST) - Alanine aminotransferase (ALT) - Alkaline
aminotransferase (AST ... aminotransferase (ALT
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