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diagnosis treatment differential vasculitis algorithm syndrome oncology guidelines lupus dermatology sle systemic classification cryoglobulinemia erythematosus hemophagocytic hlh lymphohistiocytosis summary workup
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
seen in 30—70% of cases ... connective tissue disease ... 90% • Anti-GBM disease ... antibodies #diagnosis #rheumatology ... #diseases
Rheumatoid Arthritis - ACR 2021 Guidelines - Low Disease Activity - Moderate to High Disease Activity
Guidelines - Low Disease ... Moderate to High Disease ... Rheumatoid #Arthritis #ACR2021 ... #Guidelines #management ... #treatment #rheumatology
Granulomatosis with Polyangiitis (GPA) and Microscopic Polyangiitis (MPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021
Polyangiitis (MPA) - ANCA ... Vasculitis Management ... Polyangiitis #MPA #ANCA ... #Treatment #ACR2021 ... Guidelines #algorithm #rheumatology
Eosinophilic Granulomatosis with Polyangiitis (EGPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021 Guidelines • Active
Polyangiitis (EGPA) - ANCA ... Vasculitis Management ... #Polyangiitis #ANCA ... #Treatment #ACR2021 ... Guidelines #algorithm #rheumatology
Polyarteritis Nodosa (PAN) - Vasculitis Management Algorithm - ACR/VF 2021 Guidelines • Severe Disease → Remission
) - Vasculitis Management ... Guidelines • Severe Disease ... • Non-Severe Disease ... #Treatment #ACR2021 ... Guidelines #algorithm #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... involvement: Anti-GBM Disease ... (C-ANCA): GPA > ... (P-ANCA): eGPA, ... diagnosis #algorithm #rheumatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Bone marrow disease ... Von Willebrand disease ... Cryoglobulinemia (MIXED) • ANCA ... Differential #Diagnosis #hematology ... #rheumatology #
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Nodosa (PAN), ANCA ... ) • Rheumatic Diseases ... : IgG4-Related Disease ... (SPA) • Other Causes ... Differential #Diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Diagnosis and Management ... Workup: - ANA ... Positive in 60-80% of cases ... Evolution: Chronic disease ... #Summary #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
PT, aPTT(liver disease ... function test, ANA ... bypass), LFT (liver disease ... or if a primary hematologic ... #Workup #hematology
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