14 results
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
causes development ... Particular CD4+ Th cells ... harmful -> Th Cells ... macrophages, mast cells ... #Immunology #pathophysiology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Soluble antigen - Allergen-specific ... When the specific allergen ... Hypersensitivity #Types #Classification ... #Pathophysiology ... #Allergy #Diagnosis
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Causes of Hypokalemia ... Differential Diagnosis Algorithm ... Differential #Diagnosis #Algorithm ... #causes #potassium ... #low #pathophysiology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse ... Differential Diagnosis Algorithm ... • Acne • Allergy ... Reed-Sternberg Cells ... #Causes #Hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... for secondary causes ... eosinophilia (common causes ... are asthma, allergy ... Eosinophil #Disorders #Algorithm
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Erythroderma - Diagnostic Algorithm ... Pathophysiology: ... Causes: 1) Exfoliative ... Skin-homing T-cells ... Erythroderma #Nikolsky #Algorithm
Hyperkalemia Differential Diagnosis Algorithm
R/O Pseudo-hyperkalemia:
 • Possible Lab error! Alwavs Repeat Blood sample!
 • Leukocytosis, Thrombocytosis:
Differential Diagnosis Algorithm ... Thrombocytosis: cells ... Differential #Diagnosis #Algorithm ... #causes #potassium ... #high #pathophysiology
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... lgE causes mast-cell ... T-cells recruit ... reactions #types #allergy ... #table #classification
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... (LP) tumour B cells ... Lymphoproliferative #Disorders #Classification ... #pathophysiology ... #differential #algorithm
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Differential Diagnosis Algorithm ... Cause - Decreased ... smooth muscle cells ... Differential #Diagnosis #Algorithm ... #Pathophysiology