54 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... = funny-shaped cells ... old, ~10,000 new cases ... #treatment #hematology ... #oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse ... Reed-Sternberg Cells ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Oncologic Emergencies ... Diagnosis Framework HEMATOLOGIC ... neutrophil count < 500 cells ... Constipation • Nausea ... Hyponatremia • Nausea
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Pathophysiology: ... germinative skin cells ... Causes: 1) Exfoliative ... Skin-homing T-cells ... #Diagnosis #Dermatology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophilia, 500-1,500 cells ... for secondary causes ... eosinophilia (common causes ... organ-specific signs ... Differential #diagnosis #hematology
Multiple Myeloma Diagnosis and Management Summary
Clinical Signs:
 • hyperCalcemia 28% (bone demineralization)
 • Renal disease 48%
Diagnosis and Management ... Summary Clinical Signs ... marrow plasma cells ... Myeloma #Diagnosis #Management ... #oncology
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Diagnosis and Management ... Summary Pathophysiology ... dermis Clinical Signs ... - Erosions and crusts ... #dermatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... WBC >100k, + lab signs ... Lysis of tumor cells ... TLS #diagnosis #management ... #hematology
Fat Embolism Syndrome
Trauma to the long bone or pelvis accounts for —9096 of cases. The diagnosis
the long bone or pelvis ... accounts for —9096 of cases ... Pathophysiology ... Syndrome #Diagnosis #Signs
Post-Transplantation Lymphoproliferative Disorders (PTLD)
Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
symptoms, unexplained hematologic ... EBV viral load, signs ... to 50% of PTLD cases ... Lymphoproliferative #Disorders #oncology ... #diagnosis #management