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diagnosis differential symptoms syndrome rheumatology algorithm treatment dermatology neurology hepatology disorders hemeonc nephrology vasculitis workup anemia aplastic blood bowel chronic
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm • Reactive (Inflammatory / Infectious) •
Causes of Diffuse ... • Neoplastic (Leukemia ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Lymphoblastic Leukemia ... Reed-Sternberg Cells ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
= funny-shaped cells ... old, ~10,000 new cases ... transformation to acute leukemia ... #treatment #hematology ... #oncology
Causes of Neutrophilia - Increased Neutrophils - Differential Diagnosis Algorithm Infection • Bacterial • Abscess • Viral Medications
Causes of Neutrophilia ... Chronic myelogenous leukemia ... pancytopenia, blast cells ... Diagnosis #Algorithm #Causes ... #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Rapidly rising blast cells ... -> AML: Blast crises ... : Granulocytic cells ... organs When Cancer Cells ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... Skin: - CLL cells ... or basket cells ... diagnosis #workup #oncology ... #hematology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
similarly to mast cells ... Chronic myeloid leukemia ... Chickenpox Other Causes ... Differential #Diagnosis #causes ... #hematology #basophils
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic Leukemia ... • Most common leukemia ... lymphocytes, smudge cells ... #oncology #hematology ... hemeonc #diagnosis #management
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
Oncologic Emergencies ... Diagnosis Framework HEMATOLOGIC ... neutrophil count < 500 cells ... Constipation • Nausea ... Hyponatremia • Nausea
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings Medical Comorbidities Malignancies (most commonly hairy-cell leukemia) Immunogenetic Predisposition: patient is
commonly hairy-cell leukemia ... Viral replication causes ... vascular endothelial cells ... PolyarteritisNodosa #Pathophysiology ... #Diagnosis #Signs
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