26 results
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
- Differential Diagnosis ... the total white blood ... similarly to mast cells ... during an allergic reaction ... #causes #hematology
Hyperkalemia Differential Diagnosis Algorithm
R/O Pseudo-hyperkalemia:
 • Possible Lab error! Alwavs Repeat Blood sample!
 • Leukocytosis, Thrombocytosis:
Hyperkalemia Differential Diagnosis ... Alwavs Repeat Blood ... while drawing blood ... #Algorithm #causes ... potassium #high #pathophysiology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Peripheral blood ... for secondary causes ... eosinophilia (common causes ... allergy, drug reaction ... #Differential #diagnosis
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... TRALI): Leading cause ... potassium from lysed cells ... more likely to cause ... #Transfusion #diagnosis
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Causes purpura & ... TRALI): Leading cause ... potassium from lysed cells ... more likely to cause ... #Transfusions #diagnosis
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
- Red blood cell ... with mismatched blood ... Classification #Pathophysiology ... #Allergy #Diagnosis ... #Reactions #Table
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
- Transfusion Reactions ... of high parity blood ... donor • Pathophysiology ... without other cause ... #hematology #diagnosis
Oxyhemoglobin Dissociation Curve 

Left Shift - decreased unloading of O2 at tissue level (i.e.  increased
• stored red blood ... cells - Hb variant ... Dissociation #Curve #Pathophysiology ... #Differential #Causes ... #Diagnosis
Hypoxia and Hypoxemia - Overview
Hypoxia - insufficient oxygen delivered to tissues to meet demands
Hypoxemia - low
oxygen in the blood ... oxygen in the blood ... CYTOPATHIC HYPOXIA - Cells ... #differential #diagnosis ... #causes #pathophysiology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... by blood cells ... skin that are caused ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology