49 results
Pathophysiology of Hypocomplementemic Urticarial Vasculitis

C1q/anti-C1q antibiody ->
Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology ... Cytokines, Mast Cells ... perivascular inflammatory cells ... Vasculitis #HUV #Pathophysiology ... #Rheumatology
Beta-Blockers in Cirrhosis
 • Pathophysiology
 • Indications:  Prevention of decompensation, Prevention of first variceal bleeding,
in Cirrhosis • Pathophysiology ... BetaBlockers #Cirrhosis #hepatology ... #management #pharmacology
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Pathophysiology: ... germinative skin cells ... Skin-homing T-cells ... #Diagnosis #Dermatology
Spontaneous Bacterial Peritonitis 
Clinical 
 • Fever 
 • Chills 
 • Abdominal pain 
Diagnosis
• PMN > 250 cells ... stain/culture Management ... SBP #Diagnosis #Hepatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... = funny-shaped cells ... acute leukemia Management ... MDS #Diagnosis #Management ... #treatment #hematology
Sickle Cell Disease - Pathophysiology of disease and complications 

Due to the deformed shape, HbS induces
Cell Disease - Pathophysiology ... the sickle red cells ... SickleCell #Disease #Pathophysiology ... Complications #Hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Reed-Sternberg (RS) Cells ... Lymphocyte - 5% RS cells ... (LP) tumour B cells ... Classification #pathophysiology ... #Hematology #Diagnosis
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Diagnosis and Management ... adsorption onto cancer cells ... Syndrome #Diagnosis #Management ... #treatment #hematology
Non-cirrhotic Hyperammonemia - Differential Diagnosis Framework

Hematologic & Vascular:
 • Multiple myeloma & Acute leukemia (plasma cells
Diagnosis Framework Hematologic ... leukemia (plasma cells ... Differential #Diagnosis #Pathophysiology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... Intrahepatic Cholestasis Management ... Liver #Pregnancy #hepatology ... obgyn #diagnosis #management ... #pathophysiology