12 results
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
workup for specific symptoms ... Eosinophilia, 500-1,500 cells ... organ-specific signs ... or symptoms (eg ... Differential #diagnosis #hematology
Shawl sign poikiloderma in Dermatomyositis

Poikiloderma in general is a common finding in older individuals with chronic
Shawl sign poikiloderma ... along with other signs ... and symptoms helps ... RashDecisionz #Shawl #sign ... Dermatomyositis #Dermatology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Illness Script Signs ... and symptoms: ... Anemia #diagnosis #management ... #treatment #hematology
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Diagnosis and Management ... dermis Clinical Signs ... /Symptoms/Exam findings ... erosions in ~20% Management ... #dermatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... WBC >100k, + lab signs ... Lysis of tumor cells ... TLS #diagnosis #management ... #hematology
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Diagnosis and Management ... When present, symptoms ... , signs, and complications ... PV #Diagnosis #Management ... Summary #treatment #hematology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
trunk, face or neck ... Episcleritis Signs ... and Symptoms: ... legs, face or neck ... Syndrome #diagnosis #dermatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... Skin: - CLL cells ... or basket cells ... workup #oncology #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Diagnosis: HLH signs ... and symptoms can ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
When to look for clonal/neoplastic hypereosinophilia (HEo)?
 - Exclusion of frequent causes (Drug-induced HEo, helminthiasis, cancer,
) - Clinical symptoms ... BM biopsy (Mast cells ... HEON #Diagnosis #Signs ... #Hematology #Workup