31 results
Leser–Trélat Sign on Physical Exam

Acute onset of multiple seborrheic keratoses, often a paraneoplastic sign of malignancy.

#Leser
LeserTrelat #Sign #PhysicalExam ... clinical #video #skin ... #dermatology #oncology
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
of germinative skin ... cells. ... Causes: 1) Exfoliative ... Basophils/Histamine 4) Skin-homing ... #Dermatology #Rash
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse ... Reed-Sternberg Cells ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Oncologic Emergencies ... Diagnosis Framework HEMATOLOGIC ... neutrophil count < 500 cells ... Constipation • Nausea ... Hyponatremia • Nausea
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
= funny-shaped cells ... old, ~10,000 new cases ... Management #treatment #hematology ... #oncology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophilia, 500-1,500 cells ... for secondary causes ... eosinophilia (common causes ... symptoms (eg, skin ... Differential #diagnosis #hematology
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present
rubbing of the skin ... syndrome, caused ... Nikolskys #Sign #TEN #Dermatology ... #PhysicalExam # ... Clinical #SJS #skin
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Syndrome) is a skin ... Causes: - Idiopathic ... , breast CA - Hematologic ... Syndrome #diagnosis #dermatology ... #oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Headaches • Pale skin ... and petechiae Causes ... number of CD34+ cells ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... : - CLL cells ... or basket cells ... diagnosis #workup #oncology ... #hematology