17 results
Leser–Trélat Sign on Physical Exam

Acute onset of multiple seborrheic keratoses, often a paraneoplastic sign of malignancy.

#Leser
Leser–Trélat Sign ... paraneoplastic sign ... #LeserTrelat #Sign ... #PhysicalExam # ... #dermatology #oncology
Kussmaul's Sign and Friedreich's Sign on Neck Examination

A middle-aged M with unknown PMH presents with dyspnea.
Kussmaul's Sign ... and Friedreich's Sign ... Most likely diagnosis ... #Kussmauls #Sign ... #PhysicalExam #
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present
Nikolsky's Sign ... Nikolsky's sign ... dermatological sign ... Nikolsky's sign ... #PhysicalExam #
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic ... Ill-appearing, vital sign ... sulfa-drug - Skin ... Immunocompromised #Diagnosis ... #Dermatology #Rash
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
yrs old; F>M Signs ... Anemia - Giant cells ... - Vasculitic skin ... Temporal #Arteritis #Pathophysiology ... #Diagnosis #Signs
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophilia, 500-1,500 cells ... organ-specific signs ... symptoms (eg, skin ... #Differential #diagnosis ... #hematology #eosinophilia
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Episcleritis Signs ... , breast CA - Hematologic ... Leukemia cutis Diagnosis ... Sweet #Syndrome #diagnosis ... #dermatology #oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... Hepatomegaly • Skin ... phenomenon CLL Diagnosis ... #workup #oncology ... #hematology
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
• Langerhan cells ... removal of these cells ... inflammation on skin ... Manifestations #pathophysiology ... #diagnosis #signs
Asboe-Hansen sign (also known as "indirect Nikolsky sign" or "Nikolsky II sign")

Asboe-Hansen sign is the extension
Asboe-Hansen sign ... or "Nikolsky II sign ... clinical tool for diagnosing ... #PhysicalExam # ... #skin