100 results
Sarcoidosis 
Non-caseating granulomas (Composed of T-helper & inflammatory cells) 
Clinical:
 • Disease fatal in 10% of
& inflammatory cells ... Clinical: • Disease ... • Neurologic: Bell's ... neuropathies • Skin ... Diagnosis #Symptoms #Signs
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Pathophysiology: ... of germinative skin ... cells. ... Basophils/Histamine 4) Skin-homing ... #Dermatology #Rash
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophilia, 500-1,500 cells ... glucocorticoid treatment ... organ-specific signs ... symptoms (eg, skin ... Differential #diagnosis #hematology
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Multi-system autoimmune disease ... thickening Signs ... interstitial lung disease ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
Von Willebrand Disease ... bruising • Skin ... factor VIII) Treatment ... VonWillebrand #Disease ... #Diagnosis #Hematology
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Diagnostic Algorithm Pathophysiology ... - Pathophysiology ... Ill-appearing, vital sign ... sulfa-drug - Skin ... #Diagnosis #Dermatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... Arthralgia/arthritis, Skin ... autoinflammatory diseases ... diagnosis #management #treatment ... #rheumatology
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome - Treatment ... Ulcers: • Treatment ... Skin manifestations ... #Syndrome #Treatment ... #pharmacology #rheumatology
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
yrs old; F>M Signs ... Anemia - Giant cells ... - Vasculitic skin ... Temporal #Arteritis #Pathophysiology ... #Diagnosis #Signs
Sickle Cell Disease - Pathophysiology of disease and complications 

Due to the deformed shape, HbS induces
Sickle Cell Disease ... - Pathophysiology ... the sickle red cells ... #Pathophysiology ... Complications #Hematology