28 results
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Pseudotumor - Infectious ... Non-Hodgkin's Lymphoma ... Reed-Sternberg Cells ... • Hodgkin's Lymphoma ... Causes #Hematology #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... pain, bleeding, infections ... bruising, bleeding, infection ... and secondary lymphoid ... #Oncology #Diagnosis
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm
 • Reactive (Inflammatory / Infectious)
 •
Inflammatory / Infectious ... • Neoplastic (Leukemia ... , Lymphoma, Metastatic ... Causes #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
weeks without infection ... Skin: - CLL cells ... smear: Smudge cells ... or basket cells ... diagnosis #workup #oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
e.g., HIV), EBV infection ... involved) • No leukemic ... Etiology: - Infections ... type (B cell, T cells ... NonHodgkins #comparison #oncology
Cervical Lymphadenopathy - Lymph Node Drainage
Preauricular nodes - Drain scalp, skin
 • Differential diagnosis: Scalp infections,
mycobacterial infection ... Skin neoplasm, lymphomas ... genitourinary tract, pulmonary ... head and neck, lymphomas ... , leukemias Anterior
Infection-Related Cancers
Viruses:
 • HPV - Cervical, anogenital, head and neck, skin cancer
 • HTLV-1 - Adult
Infection-Related ... - Adult T-cell Leukemia ... NHL, Hodgkin's lymphoma ... , Burkitt's lymphoma ... Associations #Cancers #oncology
Evaluation of Leukocytosis:
The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages.
Include
, monoblast, & lymphoid ... Leukemoid reaction ... ., C difficile infection ... fever, rickettsia infections ... and bacterial infections
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... = funny-shaped cells ... risk-stratification • Risks: infection ... transformation to acute leukemia ... treatment #hematology #oncology
Treatment Schema for Standard-Risk Acute Lymphoblastic Leukemia
Induction: 
 • Vincristine, Steroid (dexamethasone), L-Asparaginase, Intrathecal (IT) methotrexate
Consolidation
Lymphoblastic Leukemia ... Lymphoblastic #Leukemia ... Treatment #timeline #oncology ... #pediatrics #peds ... #management