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diagnosis hematology differential oncology hemolytic causes leukemia pancytopenia treatment workup chronic clinical cll hemeonc lymphocytic mds microscopy myelodysplastic acquired agglutinin
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Peripheral Blood ... Smear Analysis ... EricsMedicalLectures/ #Peripheral ... #Blood #Smear # ... Analysis #hematology
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Differential Diagnosis Algorithm ... Reticulocytes • Abnormal peripheral ... smear Immune-mediated ... Differential #Diagnosis #Algorithm ... #hematology
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... polychromatophilic cells ... smear changes are ... #Hematology #Pathology ... #Smear #Microscopy
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Differential Diagnosis Algorithm ... Hereditary: • Peripheral ... blood smear + DAT ... History • Bite cells ... Differential #Diagnosis #Algorithm
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... Peripheral Smear ... hemolysis, deficiency anemia ... Inflammatory Conditions: Rheumatologic ... Kawasaki, Nephrotic syndrome
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Differential Diagnosis Algorithm ... Normal Blood Smear ... Myelodysplastic Syndromes ... Macrocytosis, Target Cells ... #Causes #Hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
bone marrow and peripheral ... leukopenia) Peripheral ... Smear: • Dysplastic ... blood smear • ... #diagnosis #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Drug-associated, PCH, Evans Syndrome ... Defects: Sickle cell anemia ... Dehydrogenase ↑ - Peripheral ... Blood Smear ↑ abnormal ... Differential #Diagnosis #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... ) Labs: • Peripheral ... #oncology #hematology ... #diagnosis #management
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Differential Diagnosis Algorithm ... Sequestration Peripheral ... HLH syndrome 5. ... Acquired Aplastic Anemia ... #Hematology
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