62 results
Lelli's Test (Lever Sign) for ACL Injury

A fist is placed under the proximal 3rd of the
Lelli's Test (Lever ... #Lellis #Test #Lever ... ligament #clinical #video ... physicalexam #sports #msk
Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
to repair => Microscopic ... StressFractures #msk ... #orthopedics #pathophysiology
Lipoprotein Metabolism

Enterocytes release absorbed lipids the form of triglyceride-rich chylomicrons. These are acted upon by endothelial
by endothelial cells ... cells where they ... The liver uses this ... or supply cells ... Cholesterol #Metabolism #Pathophysiology
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
GCA is almost never ... /Symptoms: - Fever ... Anemia - Giant cells ... Temporal #Arteritis #Pathophysiology
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings
 • Subtrochanteric region spans 5 cm distally from the
femur (e. g. low level ... remodeling -> Microscopic ... Femur #Fractures #msk ... differential #causes #pathophysiology
Oxyhemoglobin Dissociation Curve 

Left Shift - decreased unloading of O2 at tissue level (i.e.  increased
of O2 at tissue level ... stored red blood cells ... of O2 at tissue level ... Dissociation #Curve #Pathophysiology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
function below injury level ... Sensory loss below level ... motor function, level ... Syndromes #diagnosis #pathophysiology ... signs #symptoms #msk
Inflammatory Joint Pain - Differential Diagnosis Algorithm 
Monoarticular
 • Gout (Podagra, Tophi)
 • Pseudogout
 • Early
• Rheumatic Fever ... polyangiitis (GPA)/microscopic ... • Rheumatic Fever ... Inflammatory #JointPain #MSK
Fever - Pyrogen Pathophysiology

EXOGENOUS PYROGEN
 • Bacteria: Lipopolysaccharide components, peptidoglycans and muramyl peptide derivatives, Toxins
 •
Fever - Pyrogen ... Pathophysiology ... Stimulate immune cells ... production → Fever ... #Fever #Pathophysiology
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
Acute Rheumatic Fever ... B and CD-4+ T cells ... inflammation • Fever ... RheumaticFever #pathophysiology