40 results
Antiarrhythmics - Vaughan Williams Classification
Class I (Ia, Ib, Ic) - Na+ Channel Blockade
 • Slows depolarization
depolarization in fast AP cells ... depolarization in slow AP cells ... depolarization in slow AP cells ... Classification #Classes #cardiology ... #pharmacology
Therapy for AL Amyloidosis 2019 
 - Antibodies (Plasma cells) 
 - Proteasome Inhibitors 
 -
Antibodies (Plasma cells ... Medications #Therapies #Pharmacology ... #Management #Classes
Oral Hypoglycemics in Diabetes Management
1  INSULIN SENSITIZER
 • TZD 
     -
Hypoglycemics in Diabetes Management ... - Stimulate β cells ... Sulfonylureas - ↑ β-cells ... Hypoglycemics #Diabetes #Management ... #pharmacology #
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Activation of CD8 T cells ... Phagocytosis of blood cells ... lymphoma, B-cell ... Lymphohistiocytosis #diagnosis #management
Drug-Induced Edema
Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
release from mast cells ... #Differential #Pharmacology ... #Pathophysiology
IDSA Recommendations for Preventing and Treating Penicillium marneffei Infections in HIV-AIDS
Preventing 1st Episode of Penicilliosis (Primary
CD4 count <100 cells ... CD4 count >100 cells ... decreases to <100 cells ... Prevention #Treatment #management ... infections #HIVAIDS #pharmacology
Anti-IL6 Agents (Tocilizumab, Siltuximab) in COVID19

IL-6 activates T cells and macrophages, among other cell types (see
-6 activates T cells ... macrophages, among other cell ... Siltuximab #COVID19 #Pharmacology ... #Management #Medications
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Antiarrhythmics Pharmacology ... increases out of cells ... ++ influx into cells ... Antiarrhythmics #Pharmacology ... Classification #Classes #pathophysiology
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
++ influx into cells ... inotropy) ACCP Cardiology ... Vaughan #Williams #Pharmacology ... Classification #Classes #pathophysiology ... #cardiology
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology
ICH Management:
1. Manage Blood Pressure
  •
Pressure (ICP) - Pathophysiology ... ICH Management ... water leaves brain cells ... Pressure #ICP #Pathophysiology ... #neurosurgery #management