37 results
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
anemia Sickled red cells ... : Sickle cell disease ... Bite cells: G6PD ... Smear #Analysis #hematology ... #microscopy #interpretation
Sickle Cell Disease - Pathophysiology of disease and complications 

Due to the deformed shape, HbS induces
Sickle Cell Disease ... - Pathophysiology ... the sickle red cells ... #Pathophysiology ... Complications #Hematology
Salmonella Aspiration on Microscopy

66 y/o male with history of coronary artery disease presents with abdominal pain.
Aspiration on Microscopy ... coronary artery disease ... CT abd/pelvis shows ... international radiology ... Salmonella #Aspiration #Microscopy
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
(LP) tumour B cells ... Responsive to Treatment ... growth, response to treatment ... Classification #pathophysiology ... #Hematology #Diagnosis
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... • Autoimmune diseases ... Adult-onset Still disease ... Unknown cause Treatment ... #summary #rheumatology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
thrombocythemia), Autoimmune disease ... adsorption onto cancer cells ... Diagnosis #Management #treatment ... #hematology #differential
Treatment of Non-hepatitis C virus Cryoglobulinemia Vasculitis - French Vasculitis Study Group

MONOCLONAL CRYOGLOBULINEMIA (TYPE 1) 
IgM
Treatment of Non-hepatitis ... Target plasma cells ... /or refractory disease ... Vasculitis #Management #Rheumatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... organ damage • Treatment ... Lysis Syndrome: • Pathophysiology ... Lysis of tumor cells ... diagnosis #management #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Cerebrovascular Disease ... , PRES Pathophysiology ... Puncture, EEG Treatment ... CNS #neurology #rheumatology ... diagnosis #management #treatment
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... increased IgG4+ cells ... " Treatment: ... IgG4 #Related #Disease ... #rheumatology