67 results
Macroglossia in Light-Chain Amyloidosis- Physical examination revealed macroglossia, with indentations from the teeth (Panel A)...A biopsy
findings confirmed a diagnosis ... under polarized microscopy ... Early diagnosis ... and treatment are ... AL #lightchain #NEJM
A non-subtle example of true Sezary syndrome.  Patient presented with erythroderma without antecedent history of
of true Sezary syndrome ... mjcascio #Sezary #Syndrome ... #Cells #Clinical ... Pathology #Smear #Microscopy ... #Hematology
Amyloidosis - Summary
Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
Diagnosis: 1. ... : • Nephrotic syndrome ... Carpal tunnel syndrome ... Increased plasma cells ... polarized light microscopy
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... only curative treatment ... #Management #treatment ... #hematology #oncology
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Hypereosinophilic Syndrome ... disorders • Diagnosis ... and Treatment Algorithm ... #HES #Hematology ... #eosinophils #diagnosis
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
factor (GCSF) treatments ... abnormal under a microscope ... marrow studies Treatment ... Immunosuppressive treatment ... #diagnosis #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... - Diagnosis and ... adsorption onto cancer cells ... vonWillebrand #Syndrome ... #treatment #hematology
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
, Sarcoidosis, Amyloidosis ... Paraprotein-associated (POEMS syndrome ... Leah Willis via ... #differential #diagnosis
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
- Differential Diagnosis ... • Fanconi's syndrome ... polyangiitis (GPA) / microscopic ... Amyloidosis) ... #Differential #Diagnosis
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
deposition disease, and amyloidosis ... diseases, CML, amyloidosis ... plasmacytoma, POEMs syndrome ... Gammopathies #MGUS #diagnosis ... #hematology #oncology