55 results
Multiple Myeloma - Treatment Algorithm
a) Newly Diagnosed Myeloma: Transplant Eligible
b) Newly Diagnosed Myeloma: Transplant Ineligible

doi: 10.1038/s41408-020-00359-2

#Multiple
- Treatment Algorithm ... a) Newly Diagnosed ... Eligible b) Newly Diagnosed ... #Treatment #Algorithm ... #management #hematology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
vasculitis • Hematologic ... criteria for 1) hematologic ... conditions - multiple myeloma ... peripheral blood myeloid ... cells NEJM Review
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Willebrand Syndrome - Diagnosis ... lymphoma, multiple myeloma ... adsorption onto cancer cells ... #Management #treatment ... #hematology #differential
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Management Summary myelo ... = funny-shaped cells ... only curative treatment ... #Management #treatment ... #hematology #oncology
Multiple Myeloma Diagnosis and Management Summary
Clinical Signs:
 • hyperCalcemia 28% (bone demineralization)
 • Renal disease 48%
Multiple Myeloma ... Diagnosis and Management ... osteolytic lesions and pathologic ... marrow plasma cells ... #Multiple #Myeloma
Herpes Zoster Mandibularis - The lesions were scattered along the area that is innervated by the
A presumptive diagnosis ... #Clinical #Photo ... #Dermatology #Herpes ... Mandibularis #Rash #NEJM
Non-cirrhotic Hyperammonemia - Differential Diagnosis Framework

Hematologic & Vascular:
 • Multiple myeloma & Acute leukemia (plasma cells
- Differential Diagnosis ... Framework Hematologic ... : • Multiple myeloma ... leukemia (plasma cells ... #Differential #Diagnosis
Myeloma: In this BM core, most plasma cells contain cytoplasmic immunoglobulin (Russell bodies).

They're difficult to identify
Myeloma: In this ... core, most plasma cells ... #Myeloma #CD138 ... BoneMarrow #Clinical #Pathology ... #Hematology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
- Differential Diagnosis ... similarly to mast cells ... Disorders: • Chronic myeloid ... #Differential #Diagnosis ... #causes #hematology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
Summary Framework Hematologic ... to IgM multiple myeloma ... to light-chain myeloma ... #Significance #hematology ... #diagnosis #oncology