36 results
management dermatology oncology clinical rheumatology differential syndrome causes algorithm hemeonc leukemia skinrash workup anemia chronic cll hemophagocytic hlh lymphocytic lymphohistiocytosis
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
thromboembolic disease ... vasculitis • Hematologic ... criteria for 1) hematologic ... peripheral blood myeloid ... cells NEJM Review
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Willebrand Syndrome - Diagnosis ... lymphoma, multiple myeloma ... thrombocythemia), Autoimmune disease ... #Management #treatment ... #hematology #differential
Multiple Myeloma Diagnosis and Management Summary Clinical Signs: • hyperCalcemia 28% (bone demineralization) • Renal disease 48%
Multiple Myeloma ... demineralization) • Renal disease ... osteolytic lesions and pathologic ... marrow plasma cells ... #Multiple #Myeloma
Castleman's Disease and Associated Syndromes HYALINE VASCULAR VARIANT • unicentric, HHV8-ve, children and young. • Hyalinized vessels
Castleman's Disease ... Diffuse plasma cells ... cell disorders (myeloma ... #Variants #Diagnosis ... #Pathology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Management Summary myelo ... = funny-shaped cells ... only curative treatment ... #Management #treatment ... #hematology #oncology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
- Differential Diagnosis ... Formation • Multiple Myeloma ... Macrocytosis, Target Cells ... • Liver Disease ... Algorithm #Causes #Hematology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
- Differential Diagnosis ... similarly to mast cells ... Colitis and Crohn’s Disease ... #Differential #Diagnosis ... #causes #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Diagnosis: • hemolytic ... significance (MGUS), CLL, Myeloma ... sensitize red blood cells ... hemolytic #anemia #hematology ... #diagnosis
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... increased IgG4+ cells ... " Treatment: ... IgG4 #Related #Disease ... #rheumatology
Secondary Syphilis Rash Secondary syphilis is the most contagious of all the stages of this disease, and
with or without treatment ... , but without treatment ... Syphilis #Rash #Diagnosis ... #Clinical #Photo ... #Dermatology
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