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clinical oncology radiology hematology leukemia mri multiple adult algorithm biopsy brain castlemans cell cilnical ct disease extramedullaryhematopoiesis honc indolent interpretation
Multiple Myeloma Diagnosis and Management Summary Clinical Signs: • hyperCalcemia 28% (bone demineralization) • Renal disease 48%
Multiple Myeloma ... Diagnosis and Management ... osteolytic lesions and pathologic ... marrow plasma cells ... #Multiple #Myeloma
Adult T-cell Leukemia / Lymphoma (ATLL) - Mimicking Angioimmunoblastic T-cell lymphoma with Hodgkin like cells Features ATLL:
with Hodgkin like cells ... Features ATLL ... Leukemia #Lymphoma #Hemepath ... #pathology #Clinical ... #diagnosis
T-LGL leukemia - T-CeIl Large Granular Lymphocytic Leukemia Clinical - Persistent (>6mo) lymphocytosis (2-20k) with proven clonality
required for dx - T-cells ... chronic LPD of NK cells ... are NK cells (sCD3 ... Lymphocytic #Leukemia #hemepath ... #pathology #diagnosis
Guide to systemic mastocytosis Criteria for diagnosis: at least 1 major and 1 minor or 3 minor
Criteria for diagnosis ... Minor: • >25% of all ... #mastocytosis #hemepath ... #pathology #algorithm ... #diagnosis #clinical
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
CML (Chronic Myeloid ... • Neutrophils (myeloid ... : Granulocytic cells ... AML (Acute Myeloid ... Hematology #Oncology #Diagnosis
Castleman's Disease and Associated Syndromes HYALINE VASCULAR VARIANT • unicentric, HHV8-ve, children and young. • Hyalinized vessels
Diffuse plasma cells ... cell disorders (myeloma ... Disease #Variants #Diagnosis ... #Pathology
Indolent T-Lymphoblastic Proliferation (iT-LBP) Features of iT-LBP: - May be seen in association with other malignancies (e.g.
Groups of TdT+ T-cells ... Proliferation #Hemepath ... #pathology #Clinical ... #diagnosis
Common MRI Sequences - Basic MRI Brain Interpretation • T1 Sequence - T1 is for anatomy.
What is pathologic ... Not all that is ... This is because all ... These swollen cells ... Neuroradiology #diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
caused by blood cells ... involve one, two, or all ... three myeloid hematopoiesis ... , and the cells ... Myelodysplastic #Syndromes #diagnosis
Raindrop Skull- ...A skeletal survey showed diffuse osteopenia, a pubic bone fracture, and numerous radiolucent lesions
characteristic of multiple myeloma ... The diagnosis was ... clonal plasma cells ... #NEJM #clinical ... raindrop #multiple #myeloma
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