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treatment differential hematology clinical syndrome causes oncology rheumatology algorithm dermatology neurology anemia leukemia workup abdominal activetb blood derm gangrenosum gastroenterology
Multiple Myeloma Diagnosis and Management Summary Clinical Signs: • hyperCalcemia 28% (bone demineralization) • Renal disease 48%
Multiple Myeloma ... Diagnosis and Management ... demineralization) • Renal disease ... osteolytic lesions and pathologic ... #Diagnosis #Management
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
thromboembolic disease ... thrombocytopenia, multiple myeloma ... conditions - multiple myeloma ... peripheral blood myeloid ... cells NEJM Review
Castleman's Disease and Associated Syndromes HYALINE VASCULAR VARIANT • unicentric, HHV8-ve, children and young. • Hyalinized vessels
Castleman's Disease ... Diffuse plasma cells ... cell disorders (myeloma ... #Variants #Diagnosis ... #Pathology
Back Pain - Differential Diagnosis Primary Back Pathology: • Musculoligamentous injury (a.k.a. lumbosacral strain) • Spondylosis (i.e.
- Differential Diagnosis ... Primary Back Pathology ... to metastatic disease ... Systemic Diseases ... , thyroid, and myeloma
IgG4-associated conditions Diagnosis of IgG4 disease is depending on BIOPSY. While IgG4 levels can be informative (and
conditions Diagnosis ... really need to see pathology ... positive plasma cells ... Even the pathology ... #differential #diagnosis
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Willebrand Syndrome - Diagnosis ... and Management ... lymphoma, multiple myeloma ... thrombocythemia), Autoimmune disease ... adsorption onto cancer cells
Etiologies of Peripheral Neuropathy • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism • Medication-induced: ART, Antibiotics,
Syphilis, Lyme disease ... POEMS syndrome, myeloma ... Charcot-Marie-Tooth, Fabry's disease ... Leah Willis via ... #differential #diagnosis
Pathologic / Fragility Fractures - Differential Diagnosis Algorithm Tumours - See Bone Lesions Scheme Paget's Disease -
Pathologic / Fragility ... - Differential Diagnosis ... - Skull/spine/Pelvis ... Fragility #Fractures #Pathologic ... #Differential #Diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
and Management ... Summary myelo ( ... = funny-shaped cells ... acute leukemia Management ... #Management #treatment
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
- Differential Diagnosis ... • Pancreatic Disease ... Formation • Multiple Myeloma ... Macrocytosis, Target Cells ... • Liver Disease
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