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diagnosis causes algorithm hematology management neurology oncology clinical hepatology infectiousdiseases peripheral secondary smear urine bloodsmear cardiology classification dermatology disorders generalized
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... , Liver diseases ... Myelodysplastic syndrome ... Hemolytic uremic syndrome ... key #diagnosis #differential
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
- Differential ... • Peripheral blood ... History • Bite cells ... malignancy, autoimmune disease ... #Differential #
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Volume (MCV) - Differential ... Algorithm Normal Blood ... Myelodysplastic Syndromes ... Macrocytosis, Target Cells ... • Liver Disease
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myeloproliferative Disease ... cells, red blood ... cells - red blood ... cells, white blood ... count with differential
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
thromboembolic disease ... Abnormalities: macrocytic anemia ... including peripheral blood ... myeloid cells ... NEJM Review: https
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
chronic kidney disease ... , Acute blood loss ... Alcohol use, Liver disease ... Myelodysplastic syndrome ... morphologic #mcv #differential
Etiologies of Peripheral Neuropathy • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism • Medication-induced: ART, Antibiotics,
DiabetesB12 deficiency, Uremia ... Syphilis, Lyme disease ... Paraprotein-associated (POEMS syndrome ... Leah Willis via ... Peripheral #Neuropathy #differential
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
fragmented red blood ... In the right photo ... seen in hemolytic anemias ... hemolytic- uremic syndromes ... Path #BloodSmear #Blood
Sickle cells These photos show sickle cells on peripheral blood smears. In the left photo target cells
blood smears. ... to sickle cell disease ... no significant anemia ... thalassemia, and HbSC disease ... Path #BloodSmear #Blood
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Iron Deficiency Anemia ... - Differential ... TSAT, sTfR • Blood ... Gastrectomy, WHDA syndrome ... Structural: Celiac disease
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