18 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... Cerebrovascular Disease ... thrombosis and/or blood-brain ... #neurology #rheumatology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... Myelodysplastic syndrome ... - Renal diseases ... Hemolytic uremic syndrome ... #differential #hematology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
thromboembolic disease ... Abnormalities: macrocytic anemia ... criteria for 1) hematologic ... including peripheral blood ... NEJM Review: https
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
inhibitors, hepatorenal syndrome ... : Disease process ... nephropathy • Secondary ... Post-infectious GN, Lupus ... Differential #Diagnosis #nephrology
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
DiabetesB12 deficiency, Uremia ... Vasculitis, Sjogren's, Lupus ... Paraprotein-associated (POEMS syndrome ... , myeloma, secondary ... Leah Willis via
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Demyelinating syndromes ... Abdominal pain (20%) Renal ... disease (30%): ... Glomerulonephritis Myositis(5%) Blood ... (75%): Anemia (
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... (-) hemolytic anemia ... to cold IgG • Lupus ... vascular beds-renal ... Paraproteinemias #Hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Classified among the secondary ... • Systemic lupus ... nervous system (CNS ... SJIA], systemic lupus ... with leukopenia, anemia
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
DDX: Rule Out Secondary ... Myeloproliferative Disease ... cells, red blood ... cells - red blood ... #diagnosis #hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
/ Systemic == Blood ... BUN: • Chronic renal ... failure/uremia ... Myelodisplastic syndrome ... Pruritus #primary #secondary