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diagnosis hematology management oncology signs aflp apml blood chronic classification crisis differentiation fatty features hepatology leukemia liver lymphocytic lymphomas lymphoproliferative
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... Diagnosis Algorithm ... Acute • Myloid ... • Lymphoid (CLL ... or λ), Smudge Cells
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... lymphoproliferative disorders ... kinase (BTK) Complications ... ’s lymphoma or acute ... leukemia • GI complications
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential ... Diagnosis Algorithm ... pattern of spread, B symptoms ... Treated Like Acute ... Classification #pathophysiology
Acute Rheumatic Fever: Pathogenesis and Clinical Findings Delayed autoimmune reaction -> Molecular mimicry -> GAS antigen cross-reacts with host ->
Acute Rheumatic ... B and CD-4+ T cells ... RheumaticFever #pathophysiology ... diagnosis #signs #symptoms ... #complications
Features of a Sickle Cell Crisis Sickle-cell disease - an autosomal recessive blood disorder. Characterized by red
recessive blood disorder ... These cells can ... The underlying pathophysiology ... 2) Aplasia - Acute ... Features #Signs #Symptoms
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... postpartum): • Initial symptoms ... ↓Antithrombin Ill ... infiltration) Differential ... Monitor and Treat Complications
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... Release from blast cells ... • Induce blast cell ... Diagnosis: >3 symptoms ... initiation • Differential
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