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differential hematology management neurology aids associated blood classification dementia differentiation disorder hand lymphomas lymphoproliferative markers myelitis neurocognitive nonhodgkin oncology syndrome
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Algorithm Acute ... • Myloid (AML ... or λ), Smudge Cells ... Amy Chung, MD, MSc ... #Algorithm
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
Disorder (HAND) ... dementia Pathophysiology ... CNS ○ Infected cells ... • Depressive symptoms ... Diagnosis: MRI
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... Release from blast cells ... : >3 symptoms, or ... • Steroids: IV ... Differentiation #Syndrome #APML
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Algorithm Hodgkin ... pattern of spread, B symptoms ... Treated Like Acute ... Amy Chung, MD, MSc ... Classification #pathophysiology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... bouts of HTN Diagnostic ... Bilateral signs and/or symptoms ... Pleocytosis > 100 cells ... simplex virus, HIV
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