26 results
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... or λ), Smudge Cells ... o CML - bcr-able ... #hematology #Markers ... #Differential #
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... adsorption onto cancer cells ... vonWillebrand #Syndrome ... Diagnosis #Management #treatment ... #hematology #differential
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... - Differential ... Responsive to Treatment ... Classification #pathophysiology ... #Hematology #Diagnosis
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... glucocorticoid treatment ... #Eosinophil #Disorders ... #Algorithm #Differential ... #diagnosis #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... organ damage • Treatment ... : • Pathophysiology ... Lysis of tumor cells ... diagnosis #management #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... Neutropenia • Platelet Disorders ... factor (GCSF) treatments ... blood count with differential ... #diagnosis #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Volume (MCV) - Differential ... • Small Bowel Disorder ... Myelodysplastic Syndromes ... Macrocytosis, Target Cells ... Algorithm #Causes #Hematology
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
HIV dementia Pathophysiology ... CNS ○ Infected cells ... The clinical syndrome ... Treatment: • HAART ... treatment • Cognitive
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Rhabdomyolysis - Differential ... iniury, Compartment syndrome ... Neuroleptic malignant syndrome ... Dermatomyositis) AKI - Pathophysiology ... per day until stable
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... Release from blast cells ... initiation • Differential